Alzheimer’s disease is a growing public health crisis in the United States. In 2025, the burden of Alzheimer’s disease continues to rise, impacting millions of Americans, their families, and the healthcare system.
According to the Alzheimer’s Association, approximately seven million Americans aged 65 and older are currently living with Alzheimer’s dementia, and this number is expected to increase dramatically in the coming years.
Key Takeaways
Prevalence of Alzheimer’s Disease
The number of Americans diagnosed with Alzheimer’s is steadily increasing. Below is an overview of Alzheimer’s prevalence by age group in 2025:
Estimated Number of Americans with Alzheimer’s by Age Group
Alzheimer’s disproportionately affects older adults, with over 73% of cases occurring in individuals aged 75 or older. The 34.6% prevalence rate among those aged 85 and older underscores the importance of early intervention.
Given that Alzheimer’s begins developing years before symptoms appear, targeted lifestyle and medical interventions in middle age (50s and 60s) could help delay or reduce future cases. Additionally, the disease impacts women at nearly twice the rate of men, which is partially attributed to longer life expectancy and potential hormonal and genetic factors.
Recent studies indicate that alternative and holistic approaches may also play a role in cognitive health. Exploring lifestyle changes, dietary habits, and natural health solutions has become increasingly popular.
Some patients are also turning to medical marijuana as a potential way to manage symptoms, with platforms like Leafy Doc connecting individuals with licensed doctors for medical cannabis evaluations.
While some research suggests cannabis may provide symptom relief, experts caution that it could also contribute to cognitive decline in older adults, making professional medical guidance essential before considering it as a treatment option.
Projected Growth of Alzheimer’s Cases
By 2050, the number of Americans aged 65+ living with Alzheimer’s is projected to reach nearly 13 million according to ALZ.
Projected Growth of Alzheimer’s Cases in the US
Key drivers of growth: Aging population, longer life expectancy, and increasing risk factors.
Mortality and Impact on Lifespan
Alzheimer’s is among the leading causes of death in the United States.
Leading Causes of Death Among Americans Aged 65+
Between 2000 and 2025, deaths from Alzheimer’s increased by 145%, while deaths from heart disease and stroke have declined as noted by NIH.
Alzheimer’s shortens life expectancy significantly. At age 70, individuals diagnosed with Alzheimer’s are twice as likely to die before age 80 compared to those without the disease.
Financial Costs of Alzheimer’s Disease
Alzheimer’s disease imposes a massive financial burden on families and the U.S. healthcare system. The total annual cost of care for people with Alzheimer’s in 2025 is projected at $412 billion.
Breakdown of Alzheimer’s Care Costs (2025, in Billions)
The $412 billion cost of Alzheimer’s care demonstrates the massive financial burden this disease places on individuals, families, and the government. Medicare and Medicaid bear 75% of these expenses, showing how dependent dementia patients are on public funding.
Out-of-pocket costs ($98 billion) also indicate that families are shouldering an increasing financial burden, particularly in home care and long-term facility expenses according to NCBI.
As cases rise, costs are projected to surpass $1 trillion by 2050, creating an unsustainable economic situation unless preventive measures, better treatments, and caregiver support programs are expanded.
The Burden on Caregivers
Alzheimer’s doesn’t just affect those diagnosed; it also places immense stress on caregivers.
Caregiving Burden for Alzheimer’s Patients
Category
Statistic
Total number of caregivers
11.5 million
Unpaid care hours provided
19.2 billion hours
The economic value of unpaid care
$420 billion
% of caregivers reporting stress
60%
% of caregivers who had to leave jobs
22%
Nearly two out of three caregivers are women, and over 30% are daughters of those they care for according to this Alzheimer’s report. 40% of caregivers report suffering from clinical depression or high stress due to caregiving demands.
Workforce Challenges and Shortage of Specialists
The demand for healthcare professionals specializing in Alzheimer’s care is increasing rapidly.
Alzheimer’s Workforce Shortage
- 55% of primary care doctors report a shortage of dementia specialists in their communities.
- By 2031, one million additional healthcare workers will be required for dementia care.
Future Outlook
Despite advancements, no cure for Alzheimer’s exists. The search for new treatments, prevention strategies, and diagnostic tools remains critical.
Current Research Efforts (2025 Update)
Research Focus
Key Findings
Blood tests for early detection
Promising, but not widely available yet
Drug therapies
New FDA-approved drugs slow disease progression
Genetic research
APOE4 gene increases risk significantly
If an effective treatment is discovered by 2030, it could save the U.S. $500 billion in healthcare costs. More than $3.8 billion in federal funding is being invested in Alzheimer’s research in 2025.
Methodology
This article was crafted using data-driven insights from the Alzheimer’s Association 2025 Facts and Figures Report, combined with supporting statistics from organizations like NIH and NCBI. We analyzed prevalence rates, financial costs, mortality trends, and caregiving burdens to present a comprehensive view of Alzheimer’s in the U.S.
The data was structured into detailed tables for clarity, with additional expert analysis beneath each dataset. All figures were cross-referenced with official public health sources to ensure accuracy. Finally, the article was designed to be accessible and informative for a broad audience, including caregivers, policymakers, and healthcare professionals.
References
- Alzheimer’s Association – 2025 Alzheimer’s Disease Facts and Figures
- Alzheimer’s Association – More than 6 Million Americans are Living with Alzheimer’s
- National Institutes of Health (NIH) – Trends in Alzheimer’s Mortality and Disease Progression
- National Center for Biotechnology Information (NCBI) – Economic Burden of Alzheimer’s Disease in the United States
- Alzheimer’s Impact Report – The Growing Burden on Family Caregivers
- Fight Chronic Disease – Alzheimer’s Disease to Cost U.S. $7.7 Trillion by 2030
