11 Most Common Preventable Diseases Affecting Older Adults in the U.S.

An elderly man with a glucose meter and various medications sits at a table, monitoring his health

The most common preventable diseases affecting older adults in the United States are hypertension, high cholesterol, heart disease, falls and related injuries, chronic lower respiratory diseases like COPD, type 2 diabetes, cancers tied to lifestyle choices, unintentional injuries, Alzheimerโ€™s disease, and vaccine-preventable infections.

To this list, experts often add oral health issues, since tooth loss, gum disease, and untreated cavities are among the most widespread but preventable problems in seniors.

According to the National Council on Aging (NCOA), nearly 80% of older Americans live with at least one chronic condition, and many juggle multiple conditions at once.

What makes this particularly striking is that most of these conditions are not an unavoidable part of aging; they are strongly linked to lifestyle, preventive healthcare, and access to timely treatment. In other words, small daily choices, about food, exercise, medication adherence, dental care, or vaccination, can reduce disease risk and extend healthy years.

1. Hypertension (High Blood Pressure)

Close-up of a healthcare provider measuring blood pressure with a sphygmomanometer
Nearly 1 in 2 adults in the U.S. has hypertension, but only about 1 in 4 has it under control

Hypertension is often called the โ€œsilent killerโ€ because it usually has no symptoms until serious complications arise.

Among Americans aged 65 and older, around 61% live with high blood pressure, and prevalence increases further with age, up to 80% in those over 75. This condition is dangerous because it silently damages blood vessels, raising the risk of stroke, kidney disease, and heart failure.

Prevention relies heavily on lifestyle habits such as lowering sodium intake, eating more fruits and vegetables, avoiding excessive alcohol, staying active, and checking blood pressure regularly.

According to the CDC, proper management can reduce the risk of stroke by 35โ€“40% and heart attack by about 25%.

Hypertension in Older Adults (Source: CDC, NCOA) Statistics
Prevalence age 65+ ~61%
Prevalence age 65โ€“74 ~72โ€“74%
Prevalence age 75+ ~83โ€“84%
Hospitalizations linked to uncontrolled BP ~500,000 annually
Stroke risk reduction with control ~35โ€“40%
Main prevention strategies Diet, physical activity, weight management, andย  routine checks

2. High Cholesterol (Hyperlipidemia)

Close-up 3D view of red blood cells flowing inside an artery, symbolizing the effects of high cholesterol
High cholesterol has no symptoms, yet it significantly increases the risk of heart attack and stroke

Cholesterol disorders affect more than half of older Americans, with about 55% of adults over 65 living with high cholesterol.

High levels of LDL cholesterol (โ€œbad cholesterolโ€) and low levels of HDL cholesterol increase the risk of atherosclerosis, which can lead to heart attacks and strokes.

The challenge is that cholesterol imbalance produces no symptoms, so many seniors do not realize they are at risk until they face a cardiac event. Prevention focuses on maintaining a balanced diet, low in saturated and trans fats and rich in fiber, along with regular exercise and avoiding tobacco.

According to the American Heart Association, reducing cholesterol even modestly can cut cardiovascular risk by 20โ€“30%.

High Cholesterol in Seniors (Source: CDC, AHA) Statistics
Prevalence age 65+ ~55%
Average cholesterol reduction with statins 20โ€“60%
Risk reduction for heart disease with statins ~25โ€“35%
Foods linked to prevention Oats, beans, nuts, fish, olive oil
Modifiable risk factors Diet, inactivity, obesity, and smoking

3. Heart Disease

Heart disease is the number one killer of older adults in the U.S., claiming nearly 695,000 lives each year. Someone dies from cardiovascular disease every 33 seconds, according to the CDC. What makes this particularly tragic is that much of the risk is preventable.

Smoking cessation, regular exercise, weight control, and managing high blood pressure and cholesterol can drastically lower heart disease risk.

Seniors who maintain an active lifestyle, even light walking, have significantly lower rates of heart-related death. Preventive screenings like electrocardiograms and cholesterol panels also detect issues early.

Heart Disease in Older Adults (Source: CDC, AHA) Statistics
Annual U.S. deaths from CVD ~695,000
Frequency of deaths 1 every 33 seconds
% of cases preventable ~80% with lifestyle changes
Common preventive strategies Smoking cessation, diet, exercise, screening
Exercise impact ~30โ€“40% reduction in cardiac risk

4. Falls and Related Injuries

Person falling backward on the ground near a broken concrete structure, representing fall-related injuries
Every year, 1 in 4 adults over 65 experiences a fall, making it the most common cause of injury in older adults

Falls are the leading cause of injury-related hospitalization in older adults. More than one in four seniors (14 million people) fall each year, according to the CDC, and 9 million of those falls result in injuries. Broken hips, traumatic brain injuries, and long-term disability are frequent outcomes.

Even a minor fall can trigger fear of falling again, which often reduces activity and leads to further decline.

Prevention includes balance and strength training, removing household tripping hazards, ensuring proper footwear, vision correction, and medication reviews to avoid dizziness.

According to the National Institute on Aging, fall-prevention programs can reduce risk by up to 30%.

Falls and Injuries (Source: CDC, NIH) Statistics
Adults 65+ experience a fall yearly 14 million+
Falls resulting in injury ~9 million
Hip fractures from falls ~75%
Hospitalizations due to falls ~800,000 annually
Prevention success (exercise programs) 20โ€“30% reduction in falls

5. Chronic Lower Respiratory Diseases (COPD)

Elderly man coughing while holding his chest, surrounded by smoke, symbolizing chronic lung disease and COPD
Chronic obstructive pulmonary disease (COPD) is the 4th leading cause of death in the United States, with smoking as the primary risk factor

COPD, including emphysema and chronic bronchitis, is primarily caused by smoking. According to the American Lung Association, smoking accounts for about 80% of COPD cases.

COPD leads to breathing difficulties, reduced lung function, and eventually dependence on oxygen therapy.

While not reversible, COPD progression can be slowed by quitting smoking, avoiding pollutants, taking prescribed medications, and staying up to date on flu and pneumonia vaccines. Pulmonary rehabilitation programs also improve quality of life.

COPD in Older Adults (Source: CDC, ALA) Statistics
% of COPD cases linked to smoking ~80%
Hospitalizations annually (all ages) ~1.5 million
Deaths from COPD annually ~150,000
Main prevention strategies No smoking, air quality protection, and vaccines

6. Type 2 Diabetes

Overweight man sitting on a couch holding a remote, symbolizing inactivity and its link to type 2 diabetes
More than 37 million Americans have diabetes, and about 90โ€“95% of them have type 2 diabetes.

Diabetes is a growing challenge among older Americans. Roughly 37 million U.S. adults live with diabetes, and nearly 8.5 million are undiagnosed.

The majority of cases are type 2, strongly tied to lifestyle factors like obesity, inactivity, and poor diet.

Prevalence is highest in older age groups, where complications such as kidney disease, vision loss, and cardiovascular disease become common.

The CDCโ€™s Diabetes Prevention Program has shown that losing just 5โ€“7% of body weight can reduce risk by 58% among prediabetic individuals.

Diabetes in Older Adults (Source: CDC, NIDDK) Statistics
Adults with diabetes (all ages) 37.3 million
Undiagnosed cases 8.5 million
Risk reduction with lifestyle changes 58%
Main preventive strategies Weight loss, activity, healthy eating

7. Cancer (Lifestyle-Linked)

Cancer remains one of the most feared conditions in old age, but nearly 40% of cancers are preventable, according to the American Cancer Society.

Smoking remains the top culprit, but obesity, poor diet, alcohol use, and physical inactivity are also major drivers.

Common preventable cancers in older adults include lung, colorectal, cervical, and skin cancer.

Regular screenings like mammograms, colonoscopies, and skin checks detect cancer early, while vaccines such as HPV can lower risk.

Preventable Cancer (Source: ACS) Statistics
Preventable cancer cases ~40%
Preventable cancer deaths ~50%
Screening effectiveness Early detection reduces mortality by up to 60%
Common modifiable factors Smoking, obesity, inactivity, diet

8. Dental and Oral Health Conditions (Often Overlooked)

Collage of a woman holding her cheek in pain and opening her mouth, highlighting dental and oral health issues
Nearly 1 in 4 adults in the U.S. has untreated tooth decay, and gum disease affects almost half of those over 30

Oral health is one of the most neglected but highly preventable health issues among older adults.

The CDC reports that nearly two-thirds of adults over 65 have gum disease, and about 20% have untreated cavities. Poor oral health is not only about tooth loss; it is linked to systemic diseases like heart disease, diabetes, and even dementia.

For example, untreated gum disease has been associated with a higher risk of Alzheimerโ€™s progression. Prevention is straightforward: daily brushing and flossing, regular dental checkups, treatment of cavities, and avoiding tobacco products according to the vipdentalny.com.

Medicare generally does not cover dental services, which is why preventive habits are especially important for seniors on fixed incomes.

Oral Health in Older Adults (Source: CDC, ADA) Statistics
Adults 65+ with gum disease ~66%
Adults 65+ with untreated cavities ~20%
Complete tooth loss (edentulism) age 65+ ~17%
Prevention strategies Brushing, flossing, dental visits, and no smoking
Link to other diseases Heart disease, diabetes, dementia

9. Unintentional Injuries (Falls, Vehicle Accidents)

Crashed cars on a city street, symbolizing unintentional injuries such as vehicle accidents and falls
Unintentional injuries rank among the top 5 leading causes of death in U.S. adults, with motor vehicle crashes and falls as the most common

Beyond falls, other unintentional injuries, like motor vehicle crashes, remain a serious issue for older adults.

Driving ability declines with vision loss, slower reflexes, and medication side effects.

According to the CDC, falls cause 56% of injury deaths in seniors, while car accidents account for another 12.5%.

Prevention involves regular driving assessments, using mobility aids, and modifying home environments to minimize hazards.

Unintentional Injuries (Source: CDC) Statistics
% of injury deaths from falls ~56%
% of injury deaths from crashes ~12.5%
Leading risk factors Vision decline, medications, home hazards
Prevention strategies Driving tests, safety modifications, mobility aids

10. Alzheimerโ€™s Disease and Dementia

Elderly person in profile with a double exposure effect showing trees over their head, symbolizing memory and dementia
About 1 in 9 adults aged 65 and older in the U.S. is living with Alzheimerโ€™s disease

Dementia affects about 6.7 million Americans over age 65. Alzheimerโ€™s disease is the most common type, accounting for 60โ€“80% of cases, as noted by the CDC.

While not entirely preventable, risk factors like high blood pressure, cholesterol, smoking, and inactivity all play a role in dementia onset.

Research also shows that staying mentally engaged, maintaining social connections, and receiving certain vaccines like shingles may reduce dementia risk by as much as 20%.

Dementia and Alzheimerโ€™s (Source: CDC, NIH) Statistics
Current dementia cases (U.S.) ~6.7 million
Expected cases by 2060 ~14 million
% risk reduction from vascular health care ~30%
Vaccination impact (shingles vaccine) ~20% risk reduction

11. Vaccine-Preventable Infections

Close-up digital illustration of a syringe needle approaching a virus particle, symbolizing vaccines preventing infections
Each year, flu and pneumonia together rank among the top 10 causes of death in older adults in the U.S

Infections like flu, pneumonia, shingles, RSV, and COVID-19 remain serious threats to older adults. According to the CDC, seasonal influenza alone leads to 140,000โ€“710,000 hospitalizations and up to 56,000 deaths annually in the U.S. Pneumococcal pneumonia and shingles also cause severe complications.

Vaccinations are among the most powerful preventive measures available. CDC guidelines recommend flu shots annually, shingles vaccines for adults over 50, pneumococcal vaccines for adults over 65, RSV vaccines for older groups, and COVID-19 boosters.

Vaccine-Preventable Conditions (Source: CDC) Statistics
Flu hospitalizations annually 140,000โ€“710,000
Flu deaths annually 12,000โ€“56,000
Pneumococcal pneumonia cases per year ~320,000
Recommended vaccines for age 65+ Flu, shingles, pneumococcal, RSV, COVID-19

Conclusion

Preventable diseases represent the greatest health challenge for older Americans. Hypertension, diabetes, oral health issues, and falls are not inevitable; they are influenced by lifestyle, preventive care, and community support.

According to the CDC and NCOA, up to 80% of chronic illnesses in older adults could be reduced or delayed through better prevention.

The lesson is clear: prevention is powerful. By taking small but consistent steps, such as controlling diet, staying active, visiting both the doctor and dentist, and keeping vaccinations up to date ,older adults can protect their independence, reduce healthcare costs, and enjoy longer, healthier lives.